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Prenatal androgen treatment does not alter the firing activity of hypothalamic arcuate kisspeptin neurons in female mice

2021-07-20

Abstract excerpt

Neuroendocrine control of reproduction is disrupted in many individuals with polycystic ovary syndrome, who present with increased luteinizing hormone (LH), and presumably gonadotropin-releasing hormone (GnRH), release frequency, and high androgen levels. Prenatal androgenization (PNA) recapitulates these phenotypes in primates and rodents. Female offspring of mice injected with dihydrotestosterone (DHT) on gestat...

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Literature Corpus work
ff9ec5b0-162f-510a-8662-a1f1fd3797c5
DOI
10.1101/2021.07.19.452845
Open publication

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Prenatal androgen treatment does not alter the firing activity of hypothalamic arcuate kisspeptin neurons in female miceDOI 10.1101/2021.07.19.452845
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