Article

Increased GABA transmission to GnRH neurons after intrahippocampal kainic acid injection in mice is sex-specific and associated with estrous cycle disruption

2022-05-21

Abstract excerpt

<h4>ABSTRACT</h4> Patients with epilepsy develop reproductive endocrine comorbidities at a rate higher than that of the general population. Clinical studies have identified disrupted luteinizing hormone (LH) release patterns in patients of both sexes, suggesting potential epilepsy-associated changes in hypothalamic gonadotropin-releasing hormone (GnRH) neuron function. In previous work, we found that GnRH neuron...

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Literature Corpus work: fcc11e0e-852b-5971-832a-cffeb096076b
DOI: 10.1101/2022.05.20.492873

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