Article

Variability vs Phenotype: multimodal analysis of Dravet Syndrome Brain Organoids powered by Deep Learning

2025-01-28

Abstract excerpt

<h4>ABSTRACT</h4> Brain organoids (BO) have risen as a reliable model for neurodelopmental disorders (ND), reproducing human brain development milestones. However, their significant intra- and inter-organoid variability compromises their use in advanced tasks such as drug testing. Overcoming experimental variability is crucial for models prone to variation, like unguided BO. BO modelling in Dravet Syndrome, a lat...

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Literature Corpus work: ff98d65d-6aa9-5003-b22e-eb0287bd926e
DOI: 10.1101/2025.01.28.635291

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