Article

Predictability of Genetic Interactions from Functional Gene Modules

2016-04-25

Abstract excerpt

Characterizing genetic interactions is crucial to understanding cellular and organismal response to gene-level perturbations. Such knowledge can inform the selection of candidate disease therapy targets. Yet experimentally determining whether genes interact is technically non-trivial and time-consuming. High-fidelity prediction of different classes of genetic interactions in multiple organisms would substantially...

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Literature Corpus work: ff9848a2-6333-5907-bd89-1403f314f0ec
DOI: 10.1101/049627

Open publication

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