Article

Motor sequence learning deficits in idiopathic Parkinson’s disease are associated with increased substantia nigra activity

2020-11-20

Abstract excerpt

Previous studies have shown that persons with Parkinson’s disease (pwPD) share specific deficits in learning new sequential movements, but the neural substrates of this impairment remain unclear. In addition, the degree to which striatal dopaminergic denervation in PD affects the cortico-striato-cerebellar motor learning network remains unknown. We aimed to answer these questions using fMRI in 16 pwPD and 16 healt...

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Literature Corpus work: ff671fdf-07eb-5a5f-abf5-4f0235bb457a
DOI: 10.1101/2020.11.19.386193

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