Article

Motor learning leverages coordinated low-frequency cortico-basal ganglia activity to optimize motor preparation in humans with Parkinson’s Disease

2024-09-15

Abstract excerpt

<h4>ABSTRACT</h4> Learning dexterous motor sequences is crucial to autonomy and quality of life but can be altered in Parkinson’s Disease (PD). Learning involves optimizing pre-movement planning (preplanning) of multiple sequence elements to reduce computational overhead during active movement. However, it is unclear which brain regions mediate preplanning or how this process evolves with learning. Recording cort...

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Literature Corpus work: 676836b3-4825-509e-8971-8ae0d59ac755
DOI: 10.1101/2024.09.13.612783

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