Article

Development in context: interferon response networks regulate human fetal thymic epithelial cell differentiation

2022-10-04

Abstract excerpt

<h4>ABSTRACT</h4> The thymus instructs T cell immunity and central tolerance, yet its therapeutic potential remains untapped. The quest to regenerate thymic function for clinical application is lagging while the signals that drive thymic epithelial cell differentiation remain incompletely understood. Here, we elucidate pathways instructing commitment and specialization of the human thymic epithelial stroma throug...

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Literature Corpus work: ff4ecb13-f55d-50d9-bd5d-c2a83d7e2e0f
DOI: 10.1101/2022.10.02.510339

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