Article
Functional analysis of the chicken PPARγ gene 5'-flanking region and C/EBPα-mediated gene regulation.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology - 1 Apr 2011
Ding Ning, Gao Yuan, Wang Ning, Li Hui
Abstract excerpt
Peroxisome proliferator-activated receptor-γ (PPARγ) and CCAAT/enhancer binding protein-α (C/EBPα) are the master regulators of adipogenesis. The regulatory mechanism of PPARγ and C/EBPα gene expression is clear in mammals, however, little is known in chicken. The aim of the present study was to characterize chicken PPARγ promoter and investigate whether PPARγ could be regulated by C/EBPα in chickens. A 2-kb...
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