Article

RNA Binding Protein TAF15 Suppresses Toxicity in a Yeast Model of FUS Proteinopathy

2021-04-22

Abstract excerpt

Mutations in Fused in Sarcoma (FUS), an RNA binding protein that functions in multiple steps in gene expression regulation and RNA processing, are known to cause familial amyotrophic lateral sclerosis (ALS). Since this discovery, mutations in several other RNA binding proteins (RBPs) have also been linked to ALS. Some of these ALS-associated RBPs have been shown to colocalize with ribonucleoprotein (RNP) granules...

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Literature Corpus work: fef69d9e-9db1-595b-b6fe-4bf9a72004fd
DOI: 10.21203/rs.3.rs-437201/v1

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