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Article

Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm.

Cell cycle (Georgetown, Tex.) - 1 Oct 2013

Shelkovnikova Tatyana A, Robinson Hannah K, Connor-Robson Natalie, Buchman Vladimir L

Abstract excerpt

Fused in sarcoma (FUS) belongs to the group of RNA-binding proteins implicated as underlying factors in amyotrophic lateral sclerosis (ALS) and certain other neurodegenerative diseases. Multiple FUS gene mutations have been linked to hereditary forms, and aggregation of FUS protein is believed to play an important role in pathogenesis of these diseases. In cultured cells, FUS variants with disease-associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24013423
DOI: 10.4161/cc.26241
PMCID: PMC3865015

Genes

FUS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm.PMID 24013423Read ↗

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