Article

Improved DNA-versus-Protein Homology Search for Protein Fossils

2021-01-26

Abstract excerpt

Protein fossils, i.e. noncoding DNA descended from coding DNA, arise frequently from transposable elements (TEs), decayed genes, and viral integrations. They can reveal, and mislead about, evolutionary history and relationships. They have been detected by comparing DNA to protein sequences, but current methods are not optimized for this task. We describe a powerful DNA-protein homology search method. We use a 64×2...

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Literature Corpus work: eec76226-512d-5531-8fd8-08fb259a758c
DOI: 10.1101/2021.01.25.428050

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