Article
Rose: generating sequence families.
Bioinformatics (Oxford, England) - 1 Jan 1998
Stoye J, Evers D, Meyer F
Abstract excerpt
MOTIVATION: We present a new probabilistic model of the evolution of RNA-, DNA-, or protein-like sequences and a software tool, Rose, that implements this model. Guided by an evolutionary tree, a family of related sequences is created from a common ancestor sequence by insertion, deletion and sub...
Topics
- Algorithms
- Amino Acid Sequence
- Base Sequence
- Computational Biology
- DNA
- Evolution, Molecular
- Humans
- Models, Genetic
- Models, Statistical
- Molecular Sequence Data
- Mutation
- Phylogeny
- Proteins