Article

Orientation-Independent-DIC imaging reveals that a transient rise in depletion force contributes to mitotic chromosome condensation

2023-11-11

Abstract excerpt

Genomic information must be faithfully transmitted into two daughter cells during mitosis. To ensure the transmission process, interphase chromatin is further condensed into mitotic chromosomes. Although protein factors like condensins and topoisomerase IIα are involved in the assembly of mitotic chromosomes, the physical bases of the condensation process remain unclear. Depletion force/macromolecular crowding, an...

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Literature Corpus work: feeeeb1d-7072-56e6-9f33-23ad84055a84
DOI: 10.1101/2023.11.11.566679

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