Article

Differential Gene Expression of Tumors Undergoing Lepidic-Acinar Transition in Lung Adenocarcinoma

2024-03-20

Abstract excerpt

<h4>ABSTRACT</h4> Lung adenocarcinoma is the most frequent subtype of thoracic malignancy, which is itself the largest contributor to cancer mortality. The lepidic subtype is a non-invasive tumor morphology, whereas the acinar subtype represents one of the invasive morphologies. This study investigates the transition from a non-invasive to an invasive subtype in the context of lung adenocarcinoma. Patients with pa...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: febb336e-890d-543d-914a-74a028357136
DOI: 10.1101/2024.03.18.24304449

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Differential Gene Expression of Tumors Undergoing Lepidic-Acinar Transition in Lung AdenocarcinomaDOI 10.1101/2024.03.18.24304449Read

A lepidic gene signature predicts patient prognosis and sensitivity to immunotherapy in lung adenocarcinoma.Semantic proximity Read

Landscape and dynamics of single tumor and immune cells in early and advanced‐stage lung adenocarcinomaSemantic proximity Read

Molecular differences across invasive lung adenocarcinoma morphological subgroupsSemantic proximity Read

An Investigation of the Immune Microenvironment and Genome during Lung Adenocarcinoma DevelopmentSemantic proximity Read

Up-regulated tumor intrinsic growth potential and decreased immune function orchestrate the evolution of lung adenocarcinomaSemantic proximity Read

Spatial transcriptomics reveals heterogeneity of histological subtypes between lepidic and acinar lung adenocarcinomaSemantic proximity Read

Single-cell and spatial transcriptome characterize coinhibitory cell-cell communications during histological progression of lung adenocarcinomaSemantic proximity Read

Archetype analysis of lung adenocarcinoma premalignancy links heterogeneity in premalignant lesions to diverging features of invasive diseaseSemantic proximity Read

Molecular characteristics, clonal relatedness and surgical outcomes of pulmonary mixed invasive mucinous and non-mucinous adenocarcinoma: a retrospective cohort study.Semantic proximity Read

Necroptosis Identifies Novel Molecular Phenotypes and Influences Tumor Immune Microenvironment of Lung Adenocarcinoma.Semantic proximity Read

Mechanisms of Progression and Heterogeneity in Multiple Nodules of Lung AdenocarcinomaSemantic proximity Read

Multi-Omics reveals SPP1+ Malignant and CXCR4+ TAM crosstalk predicts immunotherapy response in lung adenocarcinoma cancerSemantic proximity Read