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Article

A lepidic gene signature predicts patient prognosis and sensitivity to immunotherapy in lung adenocarcinoma.

Genome medicine - 12 Jan 2022

Nguyen Thinh T, Lee Hyun-Sung, Burt Bryan M, Wu Jia, Zhang Jianjun, Amos Christopher I, Cheng Chao

Abstract excerpt

BACKGROUND: Lung adenocarcinoma, the most common type of lung cancer, has a high level of morphologic heterogeneity and is composed of tumor cells of multiple histological subtypes. It has been reported that immune cell infiltration significantly impacts clinical outcomes of patients with lung adenocarcinoma. However, it is unclear whether histologic subtyping can reflect the tumor immune microenvironment, and...

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Identifiers

PMID: 35016696
DOI: 10.1186/s13073-021-01010-w
PMCID: PMC8753834

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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