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Article

Necroptosis Identifies Novel Molecular Phenotypes and Influences Tumor Immune Microenvironment of Lung Adenocarcinoma.

Frontiers in immunology - 1 Jan 2022

Zhao Chen, Xiong Kewei, Adam Abdalla, Ji Zhiqiang, Li Xiangpan

Abstract excerpt

This study aims to investigate the immune and epigenetic mutational landscape of necroptosis in lung adenocarcinoma (LUAD), identify novel molecular phenotypes, and develop a prognostic scoring system based on necroptosis regulatory molecules for a better understanding of the tumor immune microenvironment (TIME) in LUAD. Based on the Cancer Genome Atlas and Gene Expression Omnibus database, a total of 29...

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Identifiers

PMID: 35911707
DOI: 10.3389/fimmu.2022.934494
PMCID: PMC9331758

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