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Delivery of a tissue derived extracellular matrix gel modulates early fibro-adipogenic cell behavior and improves recovery following both acute and chronic atrophy muscle injury

2022-12-21

Abstract excerpt

<title>Abstract</title><p>In this study we examined the potential of muscle derived extracellular matrix (ECM) gel prepared from skeletal muscle as a treatment strategy for acute and chronic degenerative atrophy. We conducted experiments to evaluate the gel’s effectiveness in both a mouse hindlimb unloading (HU) model (disuse atrophy), and on a rabbit shoulder rotator cuff tear (RCT) model (diseased atrophy). In t...

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Literature Corpus work
1d82241c-4d71-5778-bfc4-7c50ecc771c5
DOI
10.21203/rs.3.rs-2379543/v1
Open publication

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Delivery of a tissue derived extracellular matrix gel modulates early fibro-adipogenic cell behavior and improves recovery following both acute and chronic atrophy muscle injuryDOI 10.21203/rs.3.rs-2379543/v1
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