Article

Refining the generation, interpretation, and application of multi-organ, multi-omics biological aging clocks

2025-02-07

Abstract excerpt

Multi-organ biological aging clocks derived from clinical phenotypes and neuroimaging have emerged as valuable tools for studying human aging and disease 1,2,3,4 . Plasma proteomics provides an additional molecular dimension to enrich these clocks 5 . Building on previous work 1,3 , I developed 11 multi-organ proteome-based biological age gaps (ProtBAGs) using 2448 plasma proteins from 43,498 participants in the U...

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Literature Corpus work: d7f9f70e-3b49-5246-9c9f-5257450b4695
DOI: 10.1101/2025.02.06.25321803

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