Article
Phenome-wide associations of human aging uncover sex-specific dynamics.
Nature aging - 1 Nov 2024
Reicher Lee, Bar Noam, Godneva Anastasia, Reisner Yotam, Zahavi Liron, Shahaf Nir, Dhir Raja, Weinberger Adina, Segal Eran
Abstract excerpt
Aging varies significantly among individuals of the same chronological age, indicating that biological age (BA), estimated from molecular and physiological biomarkers, may better reflect aging. Prior research has often ignored sex-specific differences in aging patterns and mainly focused on aging biomarkers from a single data modality. Here we analyze a deeply phenotyped longitudinal cohort (10K project, Israel)...
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