Article

HelD is a Global Transcription Factor Enhancing Gene Expression in Rapidly Growing Mycobacteria

2024-11-28

Abstract excerpt

<h4>ABSTRACT</h4> HelD protein, also named HelR (encoded by MSMEG_2174 in Mycobacterium smegmatis ), interacts with mycobacterial RNA polymerase (RNAP) and affects rifampicin resistance in Mycobacterium abscessus . Here, we provide data on rifampicin resistance and helD presence in the genomes of other clinically relevant nontuberculous mycobacteria. We show that helD is primarily found in rapidly growing m...

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Literature Corpus work: fe9f57ac-512f-5056-9a70-ffae6ab686c5
DOI: 10.1101/2024.11.27.625628

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