Article

Conserved Heterochromatin-like Structures with Local Regulators Mediate the Iron Stress Response in Mycobacteria

2025-08-23

Abstract excerpt

<h4>ABSTRACT</h4> Recent studies have demonstrated the importance of dynamic heterochromatin-like regions in bacterial gene regulation, particularly for adaptation to changing environments. Here, we have measured the dynamic regulatory protein-DNA landscape of the tuberculosis vaccine strain, M. bovis BCG Pasteur, under the pathogenically-relevant condition of iron starvation. Our results capture for the first t...

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Literature Corpus work: 24d966df-d882-5d77-8a4d-e7c231c6a1d2
DOI: 10.1101/2025.08.23.671944

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