Article

MAP1LC3C regulates lysosomal exocytosis and induces zinc reprogramming in renal cancer cells

2022-05-11

Abstract excerpt

MAP1LC3C (LC3C) is a member of the microtubule associated family of proteins that are essential in the formation of autophagosomes and lysosomal degradation of cargo. LC3C has tumor suppressing activity and its expression is dependent on kidney cancer tumor suppressors, such as VHL and FLCN. Recently we demonstrated that LC3C autophagy is regulated by noncannonical upstream regulatory complexes and targets for deg...

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Literature Corpus work: fe8b66ec-5810-5923-9ef2-deb4bd310b7d
DOI: 10.1101/2022.05.11.491473

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