Article

Modulating Intra-Nuclear LC3 with Small Molecules Rescues Cells from a Docetaxel-Induced Phenotype

2020-10-28

Abstract excerpt

Nucleus-associated autophagy has been described as a cellular metabolic response by which nuclear material is actively degraded. This degradation occurs after stress, such as nuclear damage or the onset of tumorigenesis. Here we describe a nucleus-associated autophagic process distinct from other forms of selective autophagy in human cell lines. We found that although nuclear localization of MAP1LC3B (LC3) is not...

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Literature Corpus work: ab84aa9d-7f76-5152-8400-5221b164b5de
DOI: 10.1101/2020.10.28.355826

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