Article

S100a4 <sup>+</sup> alveolar macrophages accelerate the progression of precancerous atypical adenomatous hyperplasia by promoting the angiogenic function regulated by fatty acid metabolism

2024-10-21

Abstract excerpt

Lung cancer is preceded by premalignant lesions, and what factors drive this transformation and the potential regulatory mode in the context of tumor initiation remain to be elucidated. In the course of precancerous lesions, we found a phasic shift in metabolic patterns. Macrophages are a heterogeneous cell population with high plasticity in the tumor microenvironment. Single-cell interaction and metabolic analyse...

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Literature Corpus work: fe3776aa-c027-5ecb-bab2-b9a844645c7b
DOI: 10.1101/2024.10.17.618873

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S100a4 <sup>+</sup> alveolar macrophages accelerate the progression of precancerous atypical adenomatous hyperplasia by promoting the angiogenic function regulated by fatty acid metabolismDOI 10.1101/2024.10.17.618873Read

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