Article

Dys-regulation of lnc-SNHG1 and miR-216b-5p correlate with chemo-resistance and indicate poor prognosis of serous epithelial ovarian cancer

2020-12-14

Abstract excerpt

<title>Abstract</title> <p><bold>Aim:</bold> This study aimed to explore whether the dysregulation of lnc-small nucleolar RNA host gene 1 (SNHG1) and miR-216b-5p correlated with chemoresistance and indicated poor prognosis of serous epithelial ovarian cancer (EOC).<bold> </bold><bold>Methods and Results: </bold> The expression of lnc-SNHG1 was upregulated, while miR-216b-5p showed low expression in patients with...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cfd2556c-9d3e-5af9-8d9c-a3fab3649122
DOI: 10.21203/rs.3.rs-58009/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dys-regulation of lnc-SNHG1 and miR-216b-5p correlate with chemo-resistance and indicate poor prognosis of serous epithelial ovarian cancerDOI 10.21203/rs.3.rs-58009/v2Read

LncRNA SNHG6 promotes chemoresistance through ULK1-induced autophagy by sponging miR-26a-5p in colorectal cancer cellsSemantic proximity Read

PRPF6 promotes metastasis and paclitaxel resistance of ovarian cancer via SNHG16/CEBPB/GATA3 axisSemantic proximity Read

LncRNA OTUD6B-AS1 promotes paclitaxel resistance in triple negative breast cancer by regulation of miR-26a-5p/MTDH pathway-mediated autophagy and genomic instabilitySemantic proximity Read

LncRNA SNHG16 modulates paclitaxel resistance in breast cancer by regulating Let-7a-5p/DUSP7Semantic proximity Read

The up-regulation of PAK2 indicates unfavorable prognosis in patients with serous epithelial ovarian cancer and contributes to paclitaxel resistance in ovarian cancer cells.Semantic proximity Read

Clinicopathological and Prognostic Value of SNHG6 in Cancers: a Systematic Review and a Meta-analysisSemantic proximity Read

Identification of Key Genes, miRNAs and miRNAs-mRNA Regulatory Pathways for Chemotherapy Resistance in Ovarian CancerSemantic proximity Read

Unveiling drug resistance pathways in high-grade serous ovarian cancer(HGSOC): recent advances and future perspectivesSemantic proximity Read

Long non-coding RNA LINC00649 regulates YES-associated protein 1 (YAP1)/Hippo pathway to accelerate gastric cancer (GC) progression via sequestering miR-16-5p.Semantic proximity Read

Downregulated m⁵C Regulator NSUN6 Enhances Proliferation, Migration and affects immune regulation in Ovarian CancerSemantic proximity Read

Novel regulatory and transcriptional networks associated with resistance to platinum-based chemotherapy in ovarian cancerSemantic proximity Read

SNHG14 promotes triple‐negative breast cancer cell proliferation, invasion, and chemoresistance by regulating the ERK / MAPK signaling pathwaySemantic proximity Read