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Article

ACSM3 suppresses the pathogenesis of high-grade serous ovarian carcinoma via promoting AMPK activity

1 Feb 2022

Abstract excerpt

PURPOSE: Ovarian carcinoma is the fifth commonest malignancy in females and exhibits a high recurrence rate. High-grade serous ovarian carcinoma (HGSOC) is the main histologic subtype. It displays extensive genetic heterogeneity. Here, we aimed to identify potential therapeutic targets for HGSOC. METHODS: Both bioinformatic data from TCGA and 73 pairs of tumor and normal samples from patients were analyzed to...

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PMID: 35124784
DOI: 10.1007/s13402-021-00658-1

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