Article

Quantification and image-derived phenotyping of retinal ganglion cell nuclei in the <i>nee</i> mouse model of congenital glaucoma

2021-04-14

Abstract excerpt

<h4>ABSTRACT</h4> The nee mouse model exhibits characteristic features of congenital glaucoma, a common cause of childhood blindness. The current study of nee mice had two components. First, the time course of neurodegeneration in nee retinal flat-mounts was studied over time using a retinal ganglion cell (RGC)-marker, BRN3A; a pan-nuclear marker, TO-PRO-3; and H&E staining. Based on segmentation of nuclei usi...

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Literature Corpus work: fd9917ce-cc99-5b9d-95ac-023562a64017
DOI: 10.1101/2021.04.13.439698

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