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Biological Correlations and Confounding Variables for Quantification of Retinal Ganglion Cells Based on Optical Coherence Tomography using Diversity Outbred Mice

2020-12-23

Abstract excerpt

<h4>Purpose</h4> Despite popularity of optical coherence tomography (OCT) in glaucoma studies, it’s unclear how well OCT-derived metrics compare to traditional measures of retinal ganglion cell (RGC) abundance. Here, Diversity Outbred (J:DO) mice are used to directly compare ganglion cell complex (GCC)-thickness measured by OCT to metrics of retinal anatomy measured ex vivo with retinal wholemounts or optic nerve...

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Literature Corpus work
5815b3cc-705a-50e0-a753-97077de891a7
DOI
10.1101/2020.12.23.423848
Open publication

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Biological Correlations and Confounding Variables for Quantification of Retinal Ganglion Cells Based on Optical Coherence Tomography using Diversity Outbred MiceDOI 10.1101/2020.12.23.423848
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