Article

Statistical Properties of Stepped Wedge Cluster-Randomized Trials in Infectious Disease Outbreaks

2020-05-06

Abstract excerpt

<h4>ABSTRACT</h4> Randomized controlled trials are crucial for the evaluation of interventions such as vaccinations, but the design and analysis of these studies during infectious disease outbreaks is complicated by statistical, ethical, and logistical factors. Attempts to resolve these complexities have led to the proposal of a variety of trial designs, including individual randomization and several types of clus...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fd61213a-d052-5540-9939-021554ba0f60
DOI: 10.1101/2020.05.01.20087429

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Statistical Properties of Stepped Wedge Cluster-Randomized Trials in Infectious Disease OutbreaksDOI 10.1101/2020.05.01.20087429Read

The required size of cluster randomized trials of non-pharmaceutical interventions in epidemic settingsSemantic proximity Read

On Small-Sample Inference in Multiphase Stepped Wedge Cluster Randomized Trial (MSW-CRT) With Binary OutcomesSemantic proximity Read

Prevalence and Methodological Characteristics of Subgroup Analyses in Stepped Wedge Cluster Randomised Trials: Protocol for a Systematic ReviewSemantic proximity Read

Using simulated infectious disease outbreaks to guide the design of individually randomized vaccine trialsSemantic proximity Read

Leveraging pathogen sequence and contact tracing data to enhance vaccine trials in emerging epidemicsSemantic proximity Read

Projeto S: A Stepped-Wedge Randomized Trial to Assess CoronaVac Effectiveness in Serrana, BrazilSemantic proximity Read

Leveraging infectious disease models to interpret randomized controlled trials: controlling enteric pathogen transmission through water, sanitation, and hygiene interventionsSemantic proximity Read

Optimal experimental designs for estimating genetic and non-genetic effects underlying infectious disease transmissionSemantic proximity Read

Optimal experimental designs for estimating genetic and non-genetic effects underlying infectious disease transmission.Semantic proximity Read

Methods and Operational Framework of the GALFLU Pragmatic Trial: Design and Feasibility of an Individually Randomized Controlled Trial Evaluating High-Dose Versus Standard-Dose Influenza Vaccination in Older AdultsSemantic proximity Read

Parallel Trends in an Unparalleled Pandemic Difference-in-differences for infectious disease policy evaluationSemantic proximity Read

A Simulation Study of Sampling in Difficult Settings: Statistical Superiority of Little-Used methodSemantic proximity Read