Article

Using simulated infectious disease outbreaks to guide the design of individually randomized vaccine trials

2021-02-01

Abstract excerpt

<h4>Background/Aims</h4> Novel strategies are needed to make vaccine efficacy trials more robust given the uncertain epidemiology of outbreaks. Spatially resolved mathematical and statistical models can help investigators identify sites at highest risk of future transmission and prioritize these for inclusion in trials. Models can also characterize the uncertainty in whether transmission will occur at a site, and...

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Literature Corpus work: fccbf00e-0847-5558-aba0-13b4d90c869b
DOI: 10.1101/2021.01.29.21250703

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