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Optimal experimental designs for estimating genetic and non-genetic effects underlying infectious disease transmission.

Genetics, selection, evolution : GSE - 5 Sept 2022

Pooley Christopher, Marion Glenn, Bishop Stephen, Doeschl-Wilson Andrea

Abstract excerpt

BACKGROUND: The spread of infectious diseases in populations is controlled by the susceptibility (propensity to acquire infection), infectivity (propensity to transmit infection), and recoverability (propensity to recover/die) of individuals. Estimating genetic risk factors for these three underlying host epidemiological traits can help reduce disease spread through genetic control strategies. Previous studies...

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PMID: 36064318
DOI: 10.1186/s12711-022-00747-1
PMCID: PMC9442948

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