Article

Leveraging pathogen sequence and contact tracing data to enhance vaccine trials in emerging epidemics

2020-09-16

Abstract excerpt

<h4>Introduction:</h4> Advance planning of the design and analysis of vaccine trials conducted during infectious disease outbreaks increases our ability to rapidly define the efficacy and potential impact of a vaccine and inform public health response. Vaccine efficacy against infectiousness (VE I ) is an important measure for understanding the full impact of a vaccine, yet it is currently not identifiable in many...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ed634c2a-f10c-5831-8b6f-29ffd4505d85
DOI: 10.1101/2020.09.14.20193789

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Leveraging pathogen sequence and contact tracing data to enhance vaccine trials in emerging epidemicsDOI 10.1101/2020.09.14.20193789Read

Analyzing Vaccine Trials in Epidemics with Mild and Asymptomatic InfectionSemantic proximity Read

Using simulated infectious disease outbreaks to guide the design of individually randomized vaccine trialsSemantic proximity Read

Optimal experimental designs for estimating genetic and non-genetic effects underlying infectious disease transmissionSemantic proximity Read

Predicting immune protection against outcomes of infectious disease from population-level effectiveness data with application to COVID-19Semantic proximity Read

Comparative Impact of Individual Quarantine vs. Active Monitoring of Contacts for the Mitigation of COVID-19: a modelling studySemantic proximity Read

Protect or prevent? A practicable framework for the dilemmas of COVID-19 vaccine prioritizationSemantic proximity Read

High-Resolution Epidemic Simulation Using Within-Host Infection and Contact DataSemantic proximity Read

EpiFusion: Joint inference of the effective reproduction number by integrating phylodynamic and epidemiological modelling with particle filteringSemantic proximity Read

Vaccine Efficacy at a Point in TimeSemantic proximity Read

Estimation of Vaccine Efficacy for Variants that Emerge After the Placebo Group Is VaccinatedSemantic proximity Read

<i>serojump</i> : A Bayesian tool for inferring infection timing and antibody kinetics from longitudinal serological dataSemantic proximity Read

Designing infection prevalence and seroprevalence surveys for learning infection dynamicsSemantic proximity Read