Article

Disruption of myelin structure and oligodendrocyte maturation in a pigtail macaque model of congenital Zika infection

2023-10-14

Abstract excerpt

Zika virus (ZikV) infection during pregnancy can cause congenital Zika syndrome (CZS) and neurodevelopmental delay in non-microcephalic infants, of which the pathogenesis remains poorly understood. We utilized an established pigtail macaque maternal-to-fetal ZikV infection/exposure model to study fetal brain pathophysiology of CZS manifesting from ZikV exposure in utero. We found prenatal ZikV exposure led to pro...

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Literature Corpus work: fd333b56-f66b-5b9b-81a1-02934dfd9c30
DOI: 10.1101/2023.10.11.561759

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