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Article

Convergence of a common solution to broad ebolavirus neutralization by glycan cap directed human antibodies

2020-10-14

Abstract excerpt

<h4>Summary</h4> Antibodies that target the glycan cap epitope on ebolavirus glycoprotein (GP) are common in the adaptive response of survivors. A subset is known to be broadly neutralizing, but the details of their epitopes and basis for neutralization is not well-understood. Here we present cryo-electron microscopy (cryo-EM) structures of several glycan cap antibodies that variably synergize with GP base-bindin...

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Identifiers and source

Literature Corpus work
fcc945a2-b0c9-552d-9ca0-671b7e32951e
DOI
10.1101/2020.10.14.340026
Open publication

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Convergence of a common solution to broad ebolavirus neutralization by glycan cap directed human antibodiesDOI 10.1101/2020.10.14.340026
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