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A broadly-neutralizing antibody against <i>Ebolavirus</i> glycoprotein that potentiates the breadth and neutralization potency of other antibodies

2024-06-25

Abstract excerpt

Ebolavirus disease (EVD) is caused by multiple species of Ebolavirus . Monoclonal antibodies (mAbs) against the virus glycoprotein (GP) are the only class of therapeutic approved for treatment of EVD caused by Zaire ebolavirus (EBOV). Therefore, mAbs targeting multiple Ebolavirus species may represent the next generation of EVD therapeutics. Broadly reactive anti-GP mAbs were produced; among these, mAbs 11886 a...

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Literature Corpus work
2b0dfe0d-323a-5cd0-a354-641852f67d64
DOI
10.1101/2024.06.21.600001
Open publication

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A broadly-neutralizing antibody against <i>Ebolavirus</i> glycoprotein that potentiates the breadth and neutralization potency of other antibodiesDOI 10.1101/2024.06.21.600001
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