Article

Relationship of <i>DUX4</i> and target gene expression in FSHD myocytes

2020-05-25

Abstract excerpt

Facioscapulohumeral dystrophy (FSHD) is linked to misexpression of the transcription factor, DUX4 . Although DUX4 target gene expression is often readily detectable, analysis of DUX4 expression has been limited due to its low expression in patient samples. Recently, single cell/nucleus RNA-sequencing was used to detect the native expression of DUX4 for the first time, but important spatial relationships with it...

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Literature Corpus work: fc61899e-0bd6-51fb-b544-91ea44a7ba56
DOI: 10.1101/2020.05.24.109710

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