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Article

Gene expression during normal and FSHD myogenesis

27 Sept 2011

Abstract excerpt

BACKGROUND: Facioscapulohumeral muscular dystrophy (FSHD) is a dominant disease linked to contraction of an array of tandem 3.3-kb repeats (D4Z4) at 4q35. Within each repeat unit is a gene, DUX4, that can encode a protein containing two homeodomains. A DUX4 transcript derived from the last repeat unit in a contracted array is associated with pathogenesis but it is unclear how. METHODS: Using exon-based...

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PMID: 21951698
DOI: 10.1186/1755-8794-4-67

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Gene expression during normal and FSHD myogenesisPMID 21951698Read ↗

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