Article

Propagated circulating tumor cells uncovers the role of NFκB and COP1 in metastasis

2022-12-11

Abstract excerpt

Circulating tumor cells (CTCs), a population of cancer cells that represents the seeds of metastatic nodules, are a promising model system for studying metastasis. However, expansion of patient-derived CTCs ex vivo is challenging and dependent on the collection of high numbers of CTCs, which are ultra-rare. Here, we report the development of a combined CTC and CTC-derived xenograft (CDX) platform for expanding an...

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Literature Corpus work: fc3d8829-e570-5c56-9236-6f1efa72b3d9
DOI: 10.1101/2022.12.09.519805

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