Article

Prenatal diagnosis of Down syndrome combined with transient abnormal myelopoiesis in foetuses with a GATA1 gene variant: Two case reports

2023-02-13

Abstract excerpt

<h4>Background: </h4> Transient abnormal myelopoiesis (TAM) is a transient haematological disorder of Down syndrome that is characterised by leucocytosis, the presence of blasts, abnormal haematopoiesis and hepatosplenomegaly. It is usually diagnosed within 8 weeks of birth, and the median age of diagnosis is 3–7 days. Case presentation We report two cases of prenatally diagnosed TAM, both with male foetal onset...

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Literature Corpus work: fc34db43-f205-5fa7-99c1-e8c938734446
DOI: 10.21203/rs.3.rs-2565345/v1

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