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Altered splicing machinery in lung carcinoids unveils NOVA1, PRPF8 and SRSF10 as novel candidates to understand tumor biology and expand biomarker discovery

2023-05-26

Abstract excerpt

<title>Abstract</title> <p><underline>Background</underline> Lung neuroendocrine neoplasms (LungNENs) comprise a heterogeneous group of tumors ranging from indolent lesions with good prognosis to highly aggressive cancers. Carcinoids are the rarest LungNENs, display low to intermediate malignancy and may be surgically managed, but show resistance to radiotherapy/chemotherapy in case of metastasis. Molecular profi...

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Literature Corpus work
fc2ee76f-f4b7-5bed-b847-e27a8741cc59
DOI
10.21203/rs.3.rs-2897773/v1
Open publication

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Altered splicing machinery in lung carcinoids unveils NOVA1, PRPF8 and SRSF10 as novel candidates to understand tumor biology and expand biomarker discoveryDOI 10.21203/rs.3.rs-2897773/v1
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