Article

Association between human blood metabolome and the risk of coronary heart disease: Mendelian randomization study

2024-02-01

Abstract excerpt

In this study, we employed Mendelian Randomization (MR) to elucidate the causal relationships between specific blood metabolites and Coronary Heart Disease (CHD). By analyzing data from Genome-Wide Association Studies (GWAS) and the FinnGen database, we conducted a two-sample MR analysis focusing on 40 metabolites and 6 metabolite ratios linked to CHD risk. Our findings highlight a group of metabolites significant...

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Literature Corpus work: fc0cc893-13a0-5d8f-9612-647f26a7cf37
DOI: 10.1101/2024.01.31.24302109

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