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Article

Causal effects between blood metabolites and myocardial infarction: A 2-sample Mendelian randomization study.

Medicine - 5 Jun 2026

Fu Yingying, Wei Aiqiu, Wu Wanjun, Peng Zheng

Abstract excerpt

Observational studies have reported associations between circulating blood metabolite features and myocardial infarction (MI), but whether these associations are causal remains uncertain. Mendelian randomization (MR) can strengthen causal inference by using genetic variants as instrumental variables. We therefore conducted a 2-sample MR study, followed by pathway enrichment analysis, to evaluate the potential...

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Identifiers

PMID: 42260813
DOI: 10.1097/MD.0000000000049161
PMCID: PMC13246053

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