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Investigating miR-214 as a pro-fibrotic mediator in renal fibrosis and its potential as a therapeutic target via effective in vivo modelling of chronic kidney disease

2020-01-01

Abstract excerpt

Chronic kidney disease (CKD) is a prevalent health condition in the UK and worldwide. CKD is defined as the progressive decline of renal filtrative capacity over time. High rates of cardiovascular dysfunction and related mortality are observed in patients with CKD. Renal fibrosis is the final common pathway though which all CKD, regardless of the initiating insult. Renal fibrosis, defined as excess collagenous mat...

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Literature Corpus work
fbcb6e7e-d4bc-5d32-922f-f6f1e8b57a24
DOI
10.7488/era/24
Open publication

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