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Article

MicroRNA-214 Antagonism Protects against Renal Fibrosis

25 Oct 2013

Abstract excerpt

Renal tubulointerstitial fibrosis is the common end point of progressive renal disease. MicroRNA (miR)-214 and miR-21 are upregulated in models of renal injury, but the function of miR-214 in this setting and the effect of its manipulation remain unknown. We assessed the effect of inhibiting miR-214 in an animal model of renal fibrosis. In mice, genetic deletion of miR-214 significantly attenuated interstitial...

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Circular RNAs in diseases
Liver Disease Diagnosis and Treatment
MicroRNA in disease regulation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24158985
DOI: 10.1681/asn.2013010072

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