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MicroRNAs and fibrosis

23 May 2012

Abstract excerpt

PURPOSE OF REVIEW: MicroRNAs (miRNAs) are short noncoding RNAs that inhibit gene expression in plants and animals. miRNAs have emerged as key players in virtually all aspects of mammalian biology. Aberrant miRNA expression is observed in numerous human diseases such as diabetes, hypercholesterolemia, cancer, and tissue fibrosis. Therefore, approaches to correct miRNA expression represent the novel therapeutic...

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PMID: 22622653
DOI: 10.1097/mnh.0b013e328354e559

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