Article

Assessments of hepatitis B virus-like particles and Crm197 as carrier proteins in melioidosis glycoconjugate vaccines

2020-04-09

Abstract excerpt

The Tier 1 select agent Burkholderia pseudomallei is the causative agent of melioidosis, a global pathogen and a major cause of pneumonia and sepsis for which no licensed vaccines currently exist. Previous work has shown the potential for Burkholderia capsular polysaccharide (CPS) to be used as a vaccine antigen but the T-cell independent nature of the immune response to this molecule requires the use of this po...

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Literature Corpus work: fbc8baf5-6f9c-5c9c-be07-b7dbc80f6b5b
DOI: 10.1101/2020.04.08.031658

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