Comparison of homologous and heterologous vaccination strategies for combating disease caused by Burkholderia pseudomallei

Abstract excerpt

Introduction Melioidosis is a major cause of disease and mortality in endemic tropical regions, and the etiologic agent, Burkholderia pseudomallei, is being isolated increasingly from an expanded range of environmental and clinical sources in locations including the United States. The disease can have multi-faceted clinical presentations and requires a complex and protracted treatment regimen which is confounded...

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