Article

MTG2: An efficient algorithm for multivariate linear mixed model analysis based on genomic information

2015-09-18

Abstract excerpt

We have developed an algorithm for genetic analysis of complex traits using genome-wide SNPs in a linear mixed model framework. Compared to current standard REML software based on the mixed model equation, our method could be more than 1000 times faster. The advantage is largest when there is only a single genetic covariance structure. The method is particularly useful for multivariate analysis, including multitra...

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Literature Corpus work: fbbcf598-164b-5cf2-95e5-710e6acc79f7
DOI: 10.1101/027201

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