Article

LiMMBo: a simple, scalable approach for linear mixed models in high-dimensional genetic association studies

2018-01-30

Abstract excerpt

Genome-wide association studies have helped to shed light on the genetic architecture of complex traits and diseases. Deep phenotyping of population cohorts is increasingly applied, where multi-to high-dimensional phenotypes are recorded in the individuals. Whilst these rich datasets provide important opportunities to analyse complex trait structures and pleiotropic effects at a genome-wide scale, existing statist...

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Literature Corpus work: 71ce6fac-9750-5cea-884a-bb4776892ece
DOI: 10.1101/255497

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