Article

Mapping Pathways to Neuronal Atrophy in Healthy, Mid-aged Adults: From Chronic Stress to Systemic Inflammation to Neurodegeneration?

2023-10-21

Abstract excerpt

Growing evidence implicates systemic inflammation in the loss of structural brain integrity in natural ageing and disorder development. Chronic stress and glucocorticoid exposure can potentiate inflammatory processes and have also been linked to neuronal atrophy, particularly in the hippocampus and the human neocortex. To improve understanding of emerging maladaptive interactions between stress and inflammation, t...

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Literature Corpus work: fbbbc1a2-fac6-5a33-a44c-088ac2b46375
DOI: 10.1101/2023.10.18.562886

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